Acrylonitrile Exposure Profile, Blood Test (0148B)

Acrylonitrile Exposure Profile, Blood Test (0148B)

Analysis Code 0148B 
Test Name Acrylonitrile Exposure Profile, Blood 
Test Includes Acetaldehyde; Acetone; Acrylonitrile; Cyanide 
Compound Synonym(s) CN; Hydrogen Cyanide; Potassium Cyanide 
Purpose Overexposure/Poisoning Determination; This test is New York State approved. 
Category Environmental/Occupation Toxin 
Method(s) Headspace Gas Chromatography (GC)
High Performance Liquid Chromatography/
TandemMass Spectrometry (LC-MS/MS) 
Specimen Requirements 3 mL Blood 
Transport Temperature Refrigerated 
Specimen Container Gray top tube (Sodium Fluoride / Potassium Oxalate) 
Special Handling Collect sample using alcohol free skin preparation. Studies have shown that cyanide has variable instability in biological specimens and is particularly unstable in some postmortem specimens. The loss of cyanide can be minimized by shipping the sample to the laboratory for analysis as soon as possible, preferably using refrigerated or frozen transportation and preservation using sodium fluoride / potassium oxalate (grey-top tube). Samples should not be refrozen if previously thawed. The potential for increases in cyanide concentrations, although rare, have also been demonstrated and may be due to microbial action. Preservation with sodium fluoride may reduce this possibility. 
Light Protection Required Not Required 
Stability Room Temperature: Undetermined
Refrigerated: Undetermined
Frozen (-20 °C): Undetermined

Acetaldehyde is an unstable compound post-collection and will both form and degrade under certain sample handling conditions. Even when extreme precautions are taken to maintain the integrity of Acetaldehyde during sample collection, transport and analysis, the results will be affected under typical collection and laboratory procedures. 
*Rejection Criteria None 
Day(s) Test Set-up / TAT [LC-MS/MS] Tuesday / 3 days
[Headspace GC] Tuesday Thursday Sunday / 3 days 
Suggested CPT Code 82600
80320 
**Minimum Volume 1.1 mL 
Test Summary Sheet Generate  

You are viewing Acrylonitrile Exposure Profile, Blood Test (0148B)
*Rejection criteria pertain to clinical specimen submissions only.
**Stated minimum volume allows for a single analysis. Repeat analysis will not be performed.


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