Acrylonitrile Exposure Profile, Blood Test (0148B)
||Acrylonitrile Exposure Profile, Blood
||Acetaldehyde; Acetone; Acrylonitrile; Cyanide
||CN; Hydrogen Cyanide; Potassium Cyanide
||Overexposure/Poisoning Determination; This test is New York State approved.
||Headspace Gas Chromatography (GC)
High Performance Liquid Chromatography/
TandemMass Spectrometry (LC-MS/MS)
||3 mL Blood
||Gray top tube (Sodium Fluoride / Potassium Oxalate)
||Collect sample using alcohol free skin preparation. Studies have shown that cyanide has variable instability in biological specimens and is particularly unstable in some postmortem specimens. The loss of cyanide can be minimized by shipping the sample to the laboratory for analysis as soon as possible, preferably using refrigerated or frozen transportation and preservation using sodium fluoride / potassium oxalate (grey-top tube). Samples should not be refrozen if previously thawed. The potential for increases in cyanide concentrations, although rare, have also been demonstrated and may be due to microbial action. Preservation with sodium fluoride may reduce this possibility.
|Light Protection Required
||Room Temperature: Undetermined
Frozen (-20 °C): Undetermined
Acetaldehyde is an unstable compound post-collection and will both form and degrade under certain sample handling conditions. Even when extreme precautions are taken to maintain the integrity of Acetaldehyde during sample collection, transport and analysis, the results will be affected under typical collection and laboratory procedures.
|Day(s) Test Set-up / TAT
||[LC-MS/MS] Tuesday / 3 days
[Headspace GC] Tuesday Thursday Sunday / 3 days
|Suggested CPT Code
|Test Summary Sheet
*Rejection criteria pertain to clinical specimen submissions only.
**Stated minimum volume allows for a single analysis. Repeat analysis will not be performed.