Busulfan, Serum/Plasma Test (0820SP)

Busulfan, Serum/Plasma Test (0820SP)

Analysis Code 0820SP 
Test Name Busulfan, Serum/Plasma 
Test Includes Busulfan 
Compound Synonym(s) Busulfex®; Myleran® 
Purpose Therapeutic Drug Monitoring; The test is an analytical service for the quantification of busulfan in a specimen. It does not provide an area-under-the-curve (AUC) calculation, busulfan clearance information or a recommendation on adjustment to dosing. This test is New York State approved. 
Category Antineoplastic 
Method(s) High Performance Liquid Chromatography/
TandemMass Spectrometry (LC-MS/MS) 
Specimen Requirements 2 mL Serum or Plasma 
Transport Temperature Frozen 
Specimen Container Plastic container (preservative-free) 
Special Handling Collect 4 mL of blood in Green top tube (Sodium Heparin).
Blood samples should be placed on wet ice immediately after collection. Centrifuge at 4 degrees Celcius within 1 hour and separate Serum or Plasma into a plastic screw capped vial using approved guidelines. The plasma, harvested into appropriate storage tube should be frozen immediately at -20 degrees Celcius and shipped frozen on dry ice. 
Light Protection Required Not Required 
Stability Room Temperature: Not Stable
Refrigerated: 7 day(s)
Frozen (-20 °C): 30 day(s) 
*Rejection Criteria Received Room Temperature. Polymer gel separation tube (SST or PST). 
Day(s) Test Set-up / TAT [LC-MS/MS] Monday 2nd Shift / 3 days 
Suggested CPT Code 80375 
**Minimum Volume 0.7 mL 
Test Summary Sheet Generate  

You are viewing Busulfan, Serum/Plasma Test (0820SP)
*Rejection criteria pertain to clinical specimen submissions only.
**Stated minimum volume allows for a single analysis. Repeat analysis will not be performed.


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