Epinephrine - Free, Plasma Test (7675P)

Epinephrine - Free, Plasma Test (7675P)

Analysis Code 7675P 
Test Name Epinephrine - Free, Plasma 
Test Includes Epinephrine 
Compound Synonym(s) Adrenaline 
Purpose Endocrinology; This test is New York State approved. 
Category Hormone 
Method(s) High Performance Liquid Chromatography/
TandemMass Spectrometry (LC-MS/MS) 
Specimen Requirements 1 mL Plasma 
Transport Temperature Frozen 
Specimen Container Green top tube (Sodium Heparin), Light Green top tube (Lithium Heparin) 
Special Handling Patient Preparation:
1. Unless the purpose of the measurement is drug monitoring, discontinue any epinephrine, norepinephrine, or dopamine injections or infusions for at least 12 hours before specimen draw.
2. Discontinue medications that release epinephrine, norepinephrine, or dopamine or hinder their metabolism for at least 1 week before obtaining the specimen. If this is not possible for medical reasons, contact the laboratory and discuss whether a shorter drug withdrawal period may be possible in a particular case. The effect of medication on catecholamines results may not be predictable.
3. Do not perform the test on patients withdrawing from legal or illegal drugs known to cause rebound plasma catecholamine release during withdrawal.
4. The patient must refrain from eating, using tobacco, and drinking caffeinated beverages, tea or alcohol for at least 4 hours before the specimen is drawn. Avoid some types of food, such as walnuts and bananas for a week prior to sampling.
5. Avoid patient stress or anxiety. Children, particularly those under 2 years of age, often show an elevated catecholamine response to stress.
6. Patient should be calm and supine in quiet surroundings for at least 30 min prior to collection.
Specimen preparation:
Draw blood into chilled blood tube (an indwelling venous catheter is advocated). Invert to mix with preservatives. Centrifuge within 30 minutes of collection (refrigerated centrifuge preferred) and transfer the plasma to labeled plastic transport tube. Freeze immediately at -20 °C and ship frozen.
Promptly centrifuge and separate Plasma into a plastic screw capped vial using approved guidelines. 
Light Protection Required Not Required 
Stability Room Temperature: Not Stable
Refrigerated: Not Stable
Frozen (-20 °C): 30 day(s) 
*Rejection Criteria Received Room Temperature. Received Refrigerated. 
Day(s) Test Set-up / TAT [LC-MS/MS] Monday Thursday / 3 days 
Suggested CPT Code 82384 
**Minimum Volume 0.4 mL 
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You are viewing Epinephrine - Free, Plasma Test (7675P)
*Rejection criteria pertain to clinical specimen submissions only.
**Stated minimum volume allows for a single analysis. Repeat analysis will not be performed.


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