Leflunomide as Metabolite (Therapeutic Drug Monitoring), Serum/Plasma Test (2531SP)
||Leflunomide as Metabolite (Therapeutic Drug Monitoring), Serum/Plasma
||Arava®; Leflunomide Metabolite
||This test is designed for the therapeutic drug monitoring of teriflunomide (leflunomide active metabolite) levels to ensure adequate dosage. The minimum reporting limit of this assay is 500 ng/mL. THIS TEST IS NOT MEANT TO MONITOR THE ELIMINATION OF TERIFLUNOMIDE IN WOMEN OF CHILDBEARING POTENTIAL WHO DISCONTINUE LEFLUNOMIDE. This test is New York State approved.
||High Performance Liquid Chromatography/
TandemMass Spectrometry (LC-MS/MS)
||1 mL Serum or Plasma
||Plastic container (preservative-free)
||Serum: Collect sample in Red top tube
Plasma: Collect sample in Lavender top tube (EDTA) or Pink top tube.
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.
|Light Protection Required
||Room Temperature: 30 day(s)
Refrigerated: 30 day(s)
Frozen (-20 °C): 1 month(s)
||Polymer gel separation tube (SST or PST).
|Day(s) Test Set-up / TAT
||[LC-MS/MS] Monday-Sunday / 7 days
|Suggested CPT Code
|Test Summary Sheet
*Rejection criteria pertain to clinical specimen submissions only.
**Stated minimum volume allows for a single analysis. Repeat analysis will not be performed.