Purpose
Therapeutic Drug Monitoring
Method(s)
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Suggested CPT Code(s)
80346
New York State Approval Status

Approved

Turnaround Time

5 days

Test Includes
1 Clonazepam Klonopin® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 2 Anticonvulsant, Antiepileptic
2 7-Amino Clonazepam Clonazepam Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 2 Hypnotic, Sedative

Test Also Known As
Rivotril®
Specimen Type
Serum or Plasma
Requested Volume
2 mL
Minimum Volume
0.7 mL
Special Handling
Serum: Collect sample in Red top tube
Plasma: Collect sample in Lavender top tube (EDTA) or Pink top tube.
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.
Specimen Container
Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature
Refrigerated
Light Protection
Not Required
Rejection Criteria
Received Room Temperature. Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical specimen submissions only.

Stability
Room Temperature: 2 day(s)
Refrigerated: 14 day(s)
Frozen (-20 °C): 1 month(s)
1 Clonazepam Klonopin® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 2 Anticonvulsant, Antiepileptic
2 7-Amino Clonazepam Clonazepam Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 2 Hypnotic, Sedative

Interface Map

LOINC® Information