Purpose
Identification and Quantitation
Method(s)
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Suggested CPT Code(s)
80364
New York State Approval Status

Approved

Known Interference(s)
Cyclopropylfentanyl [LC-MS/MS]: Crotonylfentanyl impurity
Isobutyrylfentanyl [LC-MS/MS]: beta-methylfentanyl
ortho-Fluorofentanyl [LC-MS/MS]: Ortho-fluorobutyrylfentanyl impurity
para-Fluorobutyrylfentanyl [LC-MS/MS]: meta-Fluorobutyrylfentanyl
para-Fluorofentanyl [LC-MS/MS]: Meta-fluorofentanyl
trans-3-Methylfentanyl [LC-MS/MS]: Crotonylfentanyl
Turnaround Time

5 days

Test Includes
1 Methoxyacetylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
2 4-ANPP Despropionyl fentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.1 NPS
3 THF-F Tetrahydrofuran fentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
4 meta-Methylmethoxyacetylfentanyl 3-Methylmethoxyacetylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
5 para-Methylmethoxyacetylfentanyl 4-Methylmethoxyacetylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
6 Acryl Fentanyl Acryloylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
7 para-Fluorofentanyl 4-Fluorofentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Meta-fluorofentanyl
8 ortho-Fluorofentanyl 2-Fluorofentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Ortho-fluorobutyrylfentanyl impurity
9 2-Furanylfentanyl Fu-F; Furanylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
10 U-47700 U-4 High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
11 U-49900 High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
12 U-51754 High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
13 Carfentanil Carfentanyl; Wildnil® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
14 Cyclopropylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Crotonylfentanyl impurity
15 trans-3-Methylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Crotonylfentanyl
16 cis-3-Methylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
17 Isobutyrylfentanyl Isobutyrfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS beta-methylfentanyl
18 Butyrylfentanyl Butyrfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
19 para-Fluoroisobutyrylfentanyl 4F-Isobutyrylfentanyl; FIBF High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
20 para-Fluorobutyrylfentanyl 4F-butyryl fentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS meta-Fluorobutyrylfentanyl
21 Valeryl Fentanyl Pentylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS

Specimen Type
Blood
Requested Volume
2 mL
Minimum Volume
0.7 mL
Special Handling
None
Specimen Container
Gray top tube (Sodium Fluoride / Potassium Oxalate)

Additional Collection Instructions

Transport Temperature
Frozen
Light Protection
Not Required
Rejection Criteria
Received Room Temperature. Received Refrigerated.

Rejection criteria pertain to clinical specimen submissions only.

Stability
Room Temperature: Not Stable
Refrigerated: 2 day(s)
Frozen (-20 °C): 14 day(s)
1 Methoxyacetylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
2 4-ANPP Despropionyl fentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.1 NPS
3 THF-F Tetrahydrofuran fentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
4 meta-Methylmethoxyacetylfentanyl 3-Methylmethoxyacetylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
5 para-Methylmethoxyacetylfentanyl 4-Methylmethoxyacetylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
6 Acryl Fentanyl Acryloylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
7 para-Fluorofentanyl 4-Fluorofentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Meta-fluorofentanyl
8 ortho-Fluorofentanyl 2-Fluorofentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Ortho-fluorobutyrylfentanyl impurity
9 2-Furanylfentanyl Fu-F; Furanylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
10 U-47700 U-4 High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
11 U-49900 High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
12 U-51754 High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
13 Carfentanil Carfentanyl; Wildnil® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
14 Cyclopropylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Crotonylfentanyl impurity
15 trans-3-Methylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS Crotonylfentanyl
16 cis-3-Methylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
17 Isobutyrylfentanyl Isobutyrfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS beta-methylfentanyl
18 Butyrylfentanyl Butyrfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
19 para-Fluoroisobutyrylfentanyl 4F-Isobutyrylfentanyl; FIBF High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS
20 para-Fluorobutyrylfentanyl 4F-butyryl fentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS meta-Fluorobutyrylfentanyl
21 Valeryl Fentanyl Pentylfentanyl High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/mL 0.05 NPS

Interface Map

LOINC® Information