Purpose
Detection of in utero exposure to drugs of abuse consistent with maternal use during the second and third trimesters of pregnancy; Newborn (neonatal) toxicology
Method(s)
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Suggested CPT Code(s)
80307
New York State Approval Status

Approved

Turnaround Time

1 days (If Positive: 3 days)

Test Includes
1 6-Monoacetylmorphine - Free 6-MAM; Heroin Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.2
2 7-Amino Clonazepam Clonazepam Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Hypnotic, Sedative
3 Alprazolam Xanax® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anxiolytic, Sedative
4 Amphetamine Benzphetamine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Anorexigenic, Stimulant
5 Benzoylecgonine Cocaine Degradation Product High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Stimulant
6 Butalbital High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Hypnotic, Sedative
7 Clonazepam Klonopin® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anticonvulsant, Antiepileptic
8 Codeine - Free High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Narcotic Analgesic
9 Delta-9 Carboxy THC Inactive Metabolite of Delta-9 THC High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.1 Cannabinoid
10 Diazepam Valium® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anxiolytic, Sedative
11 EDDP Methadone Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Narcotic Analgesic
12 Fentanyl Duragesic®; Sublimaze® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Anesthetic, Opioid Analgesic
13 Hydrocodone - Free Vicodin®; Zohydro® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Narcotic Analgesic
14 Hydromorphone - Free Dilaudid®; Hydrocodone Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Narcotic Analgesic
15 MDA 3,4-Methylenedioxyamphetamine; Adam; MDMA Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Stimulant
16 MDEA 3,4-methylenedioxyethylamphetamine; Eve High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Stimulant
17 MDMA 3,4-Methylenedioxymethamphetamine; Ecstasy High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Stimulant
18 Meperidine Demerol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Analgesic, Anesthetic
19 Methadone Dolophine® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Narcotic Analgesic
20 Methamphetamine Benzphetamine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Stimulant
21 Midazolam Versed® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anxiolytic, Sedative
22 Morphine - Free High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Narcotic Analgesic
23 Nordiazepam Chlordiazepoxide Metabolite; Diazepam Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anxiolytic, Sedative
24 Norfentanyl Fentanyl Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Anesthetic, Opioid Analgesic
25 Normeperidine Meperidine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Analgesic, Anesthetic
26 Oxazepam Diazepam Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anxiolytic, Sedative
27 Oxycodone - Free OxyContin®; Roxicodone® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.5 Narcotic Analgesic
28 Oxymorphone - Free Numorphan®; Opana®; Oxycodone Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 0.2 Narcotic Analgesic
29 Phencyclidine Angel Dust; Sherm; PCP High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 1.0 Hallucinogen
30 Phenobarbital Luminal® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 5 Anticonvulsant, Sedative
31 Temazepam Diazepam Metabolite; Normison® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Anxiolytic, Sedative
32 Tramadol Ultram®; Ultrex® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Analgesic, Anti-Inflammatory
33 Zolpidem Ambien® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) ng/g 2 Hypnotic, Sedative

Test Also Known As
Neonatal
Reflex Tests
Test Code Test Name
52342UC Barbiturates Confirmation (Qualitative), Umbilical Cord Tissue
52345UC Amphetamines Confirmation (Qualitative), Umbilical Cord Tissue
52354UC Fentanyl and Metabolite Confirmation (Qualitative), Umbilical Cord Tissue
52355UC Meperidine and Metabolite Confirmation (Qualitative), Umbilical Cord Tissue
52356UC Methadone and Metabolite Confirmation (Qualitative), Umbilical Cord Tissue
52357UC Phencyclidine Confirmation (Qualitative), Umbilical Cord Tissue
52358UC Zolpidem Confirmation (Qualitative), Umbilical Cord Tissue
52359UC Opiates - Free (Unconjugated) Confirmation (Qualitative), Umbilical Cord Tissue
52360UC Benzodiazepines Confirmation (Qualitative), Umbilical Cord Tissue
52361UC Tramadol Confirmation (Qualitative), Umbilical Cord Tissue
52362UC Cannabinoids Confirmation (Qualitative), Umbilical Cord Tissue
52363UC Cocaine Metabolite Confirmation (Qualitative), Umbilical Cord Tissue
Compliance Statement
This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the US Food and Drug Administration.
Sample Type
Umbilical Cord
Requested Volume
10 g
Minimum Volume
10 g
Special Handling
Collect at least 6 inches of umbilical cord (approximately the length of an adult hand). Drain and discard any blood. Rinse the exterior of the cord segment with normal saline or sterile water. Pat the cord dry and place in container for transport. Store at refrigerated temperature.



Unacceptable Specimens: Cords soaking in blood or other fluid. Formalin fixed. Tissue that is obviously decomposed. Samples received without cold pack.
Sample Container
Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature
Refrigerated
Light Protection
Not Required
Rejection Criteria
None

Rejection criteria pertain to clinical sample submissions only.

Stability
Room Temperature: Undetermined
Refrigerated: 7 day(s)
Frozen (-20 °C): 14 day(s)

The CPT Codes provided in this document are based on AMA Guidelines and are for informational purposes only. NMS Labs Does not assume responsibility for billing errors due to Reliance on the CPT Codes listed in this document.

*The information contained in this document represents database configurations, as they will appear on the effective date listed above.