Purpose
Therapeutic Drug Monitoring
Method(s)
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Suggested CPT Code(s)
80156
80157x2
New York State Approval Status

Approved

Turnaround Time

8 days

Test Includes
1 Carbamazepine-10,11-Epoxide - Free Carbamazepine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
2 Carbamazepine - Free Tegretol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
3 Carbamazepine-10,11-Epoxide - Total Carbamazepine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
4 Carbamazepine - Total Tegretol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
5 Carbamazepine-10,11-Epoxide - Bound Carbamazepine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2
6 Carbamazepine - Bound Tegretol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2

Test Also Known As
Epitol®
Specimen Type
Serum or Plasma
Requested Volume
2 mL
Minimum Volume
1.0 mL
Special Handling
Serum: Collect sample in Red top tube
Plasma: Collect sample in Lavender top tube (EDTA) or Pink top tube.
Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial using approved guidelines.
Specimen Container
Plastic container (preservative-free)

Additional Collection Instructions

Transport Temperature
Refrigerated
Light Protection
Not Required
Rejection Criteria
Polymer gel separation tube (SST or PST).

Rejection criteria pertain to clinical specimen submissions only.

Stability
Room Temperature: Undetermined
Refrigerated: 22 day(s)
Frozen (-20 °C): Undetermined
1 Carbamazepine-10,11-Epoxide - Free Carbamazepine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
2 Carbamazepine - Free Tegretol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
3 Carbamazepine-10,11-Epoxide - Total Carbamazepine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
4 Carbamazepine - Total Tegretol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2 Anticonvulsant, Antiepileptic
5 Carbamazepine-10,11-Epoxide - Bound Carbamazepine Metabolite High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2
6 Carbamazepine - Bound Tegretol® High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.2

Interface Map

LOINC® Information