Purpose
Forensic Analysis; Exclusion Screen
Method(s)
Enzyme-Linked Immunosorbent Assay (ELISA)
Headspace Gas Chromatography (GC)
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Spectrophotometry (SP)
Suggested CPT Code(s)
80307x3
83050
83060
84600
New York State Approval Status

Approved

Turnaround Time

8 days (If Positive: 15 days)

Test Includes
1 Cyanide CN; Hydrogen Cyanide; Potassium Cyanide High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.1 Environmental/Occupation Toxin
2 Opiates Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Narcotic Analgesic
3 Cocaine / Metabolites Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Stimulant
4 Benzodiazepines Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 100 Anxiolytic, Sedative
5 Cannabinoids Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 10 Cannabinoid
6 Amphetamines Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Stimulant, Anorexogenic
7 Barbiturates Enzyme-Linked Immunosorbent Assay (ELISA) mcg/mL 0.04 Hypnotic, Sedative
8 Methadone / Metabolite Dolophine® Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 25 Narcotic Analgesic
9 Phencyclidine Angel Dust; PCP; Sherm Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 10
10 Buprenorphine / Metabolite Buprenex®; Suboxone®; Subutex®; Temgesic® Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 0.5 Narcotic Analgesic
11 Methamphetamine / MDMA Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Stimulant
12 Oxycodone / Oxymorphone Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 10 Narcotic Analgesic
13 Fentanyl / Acetyl Fentanyl Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 0.5 Anesthetic, Opioid Analgesic
14 Volatiles Headspace Gas Chromatography (GC) Environmental/Occupation Toxin
15 Carboxyhemoglobin COHb Spectrophotometry (SP) %Saturation 5 Biological Marker (Exposure)
16 Methemoglobin Spectrophotometry (SP) %Saturation 1 Biological Marker (Exposure)
17 Sulfhemoglobin Spectrophotometry (SP) %Saturation 2 Biological Marker (Exposure)

Reflex Tests
Test Code Test Name
52167B Buprenorphine and Metabolite - Free (Unconjugated) Confirmation, Blood
52484B Fentanyl and Acetyl Fentanyl Confirmation, Blood
5636B Cyanide Confirmation, Blood
5637B Cocaine and Metabolites Confirmation, Blood
5641B Benzodiazepines Confirmation, Blood
5645B Opiates - Free (Unconjugated) Confirmation, Blood
5646B Cannabinoids Confirmation, Blood
5651B Barbiturates Confirmation, Blood
5654B Carbon Monoxide Exposure Biouptake Confirmation, Blood
5657B Phencyclidine Confirmation, Blood
5682B Methadone and Metabolite Confirmation, Blood
5684B Amphetamines Confirmation, Blood
Specimen Type
Blood
Requested Volume
10 mL
Minimum Volume
4.8 mL
Special Handling
Studies have shown that cyanide has variable instability in biological specimens and is particularly unstable in some postmortem specimens. The loss of cyanide can be minimized by shipping the sample to the laboratory for analysis as soon as possible, preferably using refrigerated or frozen transportation and preservation using sodium fluoride / potassium oxalate (grey-top tube). Samples should not be refrozen if previously thawed. The potential for increases in cyanide concentrations, although rare, have also been demonstrated and may be due to microbial action. Preservation with sodium fluoride may reduce this possibility.
Specimen Container
Gray top tube (Sodium Fluoride / Potassium Oxalate), Lavender top tube (EDTA)

Additional Collection Instructions

Transport Temperature
Refrigerated
Light Protection
Not Required
Rejection Criteria
None

Rejection criteria pertain to clinical specimen submissions only.

Stability
Room Temperature: Undetermined
Refrigerated: Undetermined
Frozen (-20 °C): Undetermined
1 Cyanide CN; Hydrogen Cyanide; Potassium Cyanide High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS) mcg/mL 0.1 Environmental/Occupation Toxin
2 Opiates Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Narcotic Analgesic
3 Cocaine / Metabolites Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Stimulant
4 Benzodiazepines Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 100 Anxiolytic, Sedative
5 Cannabinoids Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 10 Cannabinoid
6 Amphetamines Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Stimulant, Anorexogenic
7 Barbiturates Enzyme-Linked Immunosorbent Assay (ELISA) mcg/mL 0.04 Hypnotic, Sedative
8 Methadone / Metabolite Dolophine® Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 25 Narcotic Analgesic
9 Phencyclidine Angel Dust; PCP; Sherm Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 10
10 Buprenorphine / Metabolite Buprenex®; Suboxone®; Subutex®; Temgesic® Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 0.5 Narcotic Analgesic
11 Methamphetamine / MDMA Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 20 Stimulant
12 Oxycodone / Oxymorphone Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 10 Narcotic Analgesic
13 Fentanyl / Acetyl Fentanyl Enzyme-Linked Immunosorbent Assay (ELISA) ng/mL 0.5 Anesthetic, Opioid Analgesic
14 Volatiles Headspace Gas Chromatography (GC) Environmental/Occupation Toxin
15 Carboxyhemoglobin COHb Spectrophotometry (SP) %Saturation 5 Biological Marker (Exposure)
16 Methemoglobin Spectrophotometry (SP) %Saturation 1 Biological Marker (Exposure)
17 Sulfhemoglobin Spectrophotometry (SP) %Saturation 2 Biological Marker (Exposure)

Interface Map

LOINC® Information